Center of Excellence

Meharry Medical College

With a strong commitment to advancing human health, the COE advances translational, community-based, and multi-center clinical research focused on improving prevention, treatment, access, and outcomes for underserved populations.

About the center

Meharry Medical College’s Center of Excellence (COE) for Clinical and Translational Research transforms scientific discovery into meaningful action for the communities that need it most. With a strong commitment to advancing human health, the COE advances translational, community-based, and multi-center clinical research focused on improving prevention, treatment, access, and outcomes for underserved populations.

The Center provides comprehensive support to investigators across all phases of clinical research and across clinical specialties. From study feasibility review and protocol design to regulatory preparation, participant recruitment, data collection, biological sample processing, and research implementation, the Center serves as a trusted partner in moving research from concept to completion.

Its robust infrastructure includes regulatory and ethics support, biostatistics, workforce development, sample processing, research pharmacy services, CITI-trained nursing staff, outpatient and hospital-based research support, and monthly translational research training. Through community-engaged partnerships, the Center also connects volunteers to clinical trial opportunities, including ResearchMatch, and helps ensure that diverse communities are represented in research that shapes the future of health care

Latest News & Updates

Clinical Trials & Research

The Center has supported major research initiatives including EMERGE, PREVENTABLE, COVID-19 vaccine trials, IGNITE clinical trials such as GUARDD-US and ADOPT PGx, cancer interventional and screening trials, PCORI comparative effectiveness trials, sepsis biomarker studies, APS Consortium studies, and the GREAT Study.

By preparing investigators, strengthening collaboration, and expanding access to clinical trials, Meharry’s Center of Excellence for Clinical and Translational Research accelerates research that delivers real-world impact and advances health equity for all.

GREAT Study

Meharry is leading the Genomics REsearch Advancing Transformational (GREAT) health Study. The GREAT Study is a large research initiative at Meharry that aims to better understand how gene variants influence chronic diseases and health disparities by recruiting diverse participants and advancing more equitable, precision-focused prevention and treatment strategies.

PROACTION

PROspective ACcrual to Investigate reprOductive cancers in women (Genomic biomarkers in endometrial Cancer) : PROACTION is a prospective research study focused on reproductive cancers in women, especially endometrial cancer. It examines genomic biomarkers that may improve early detection, risk stratification, and understanding of disease biology to support more personalized and effective approaches to care.

PERSEPHONE

This clinical trial is evaluating the safety, effectiveness, and tolerability of lunsekimig, an investigational medication, in adults aged 40–80 with inadequately controlled chronic obstructive pulmonary disease (COPD) associated with higher levels of a specific type of white blood cell linked to inflammation. Participants will be randomly assigned to receive subcutaneous lunsekimig or placebo during a 48-week treatment. The goal is to determine whether lunsekimig can improve COPD outcomes compared with placebo.

EXPrESSIVE

The EXPrESSIVE clinical research study is comparing a monthly oral tablet to the commercially available once-a-day pill for HIV PrEP (pre-exposure prophylaxis). Conducted in a randomized, double-blind fashion, this trial is evaluating the safety, efficacy, and tolerability of the monthly tablet. It serves to expand prevention options for people at a high risk of HIV acquisition.

To contact Meharry Medical College regarding clinical trials, contact Dr. Rajbir Singh (rsingh@mmc.edu).

Leadership & Fellows

Rajbir Singh

Dr. Rajbir Singh

Executive Director, Center of Excellence for Clinical and Translational Research
John-Oleis-D.Ph

John Oleis, D.Ph.

Clinical Research Pharmacist
Barbara Dailey

Barbara D. Dailey, RN, BSN, MSP

Program Manager, The Great Study
Cassandra Wheeler

Cassandra Wheeler, DNP, APRN, FNP-BC

Clinical Research Nurse Practitioner
Cassandra White, MS, CCMA

Cassandra White, MS, CCMA

Research Coordinator I
Kayla Bean, MHS, CPT

Kayla Bean, MHS, CPT

Clinical Research Coordinator I
Kristen Weir

Kristen Weir, RN

Clinical Research Coordinator II
Muddather Babiker

Muddather Babiker

Participant Data Manager
Tamela Ensrud

Tamela Ensrud

Sponsor Liaison
Timothy Jacobs

Timothy Jacobs

Research Assistant
Tobi Oguntoyinbo, MS

Tobi Oguntoyinbo, MS

Clinical Research Coordinator I
Yvette Burgess

Yvette Burgess, MBA

Program Coordinator
Abraham Garcia Ortega, MD

Abraham Garcia Ortega, MD

Clinical Research Coordinator II
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Glory S. Stanton, BS, MA

Clinical Research Coordinator II
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Sonja V. White, Pharm.D.

Clinical Research Coordinator II, Research Pharmacist
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Judy McDonough

Clinical Research Coordinator I
Anaite Montes Bu

Anaite Montes, MS

Clinical Research Data Analyst
Carol G.

Carol Gutierrez

Clinical Research Coordinator II
Hannah Connelly

Hannah Connelly

Clinical Research Coordinator I
Jennifer Bethune

Jen Bethune, LPN, CHC

Clinical Research Coordinator II
April Hill Jackson

April Hill-Jackson

Community Engagement Coordinator
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